2026 NFL Odds Week 4: Lines, Spreads, Results For All 16 Games

All that remains in Week 3 is a Monday Night Football matchup between the Eagles and Bears, before Week 4 kicks off with a Thursday tilt between the Steelers and Browns. Here are the lines for every Week 4 matchup at bet365 Sportsbook as of Sept. 27. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports. Spread: Steelers -2.5Moneyline: Steelers -150, Browns +125O/U: 38.5 Spread: Colts -3.5Moneyline: Colts -200, Commanders +165O/U: 47.5 Spread: Giants -2.5Moneyline: Giants -135, Cardinals +115O/U: 43.5 Spread: Texans -1.5Moneyline: Texans -130, Cowboys +110O/U: 46.5 Spread: TBDMoneyline: TBDO/U: TBD Spread: Bengals -2.5Moneyline: Bengals -140, Jaguars +120O/U: 49.5 Spread: Rams -2.5Moneyline: Rams -150, Eagles +125O/U: 45.5 Spread: Bills -6.5Moneyline: Bills -310, Patriots +250O/U: 48.5 Spread: Bears -2.5Moneyline: Bears -160, Jets +135O/U: 42.5 Spread: Ravens -11.5Moneyline: Ravens -750, Titans +525O/U: 43.5 Spread: Vikings -10.5Moneyline: Vikings -700, Dolphins +500O/U: 42.5 Spread: 49ers -2.5Moneyline: 49ers -160, Broncos +135O/U: 45.5 Spread: Chiefs -5.5Moneyline: Chiefs -250, Raiders +205O/U: 45.5 Spread: Seahakws -6.5Moneyline: Seahawks -310, Chargers +250O/U: 44.5 Spread: Lions -2.5Moneyline: Lions -155, Panthers +130O/U: 46.5 Spread: Saints -2.5Moneyline: Saints -155, Falcons +130O/U: 46.5​Check out the odds for every NFL Week 4 contest.